1st International Kawasaki Disease Registry
& EUROKiDs Joint Meeting
November 2–4, 2023
Bologna, Italy
Inflammation and the Young Heart
Through the Lens of MIS-C and Kawasaki Disease
Cardiology and Rheumatology Perspectives
Programme
Thursday / 2 november 2023
Brian McCrindle (Toronto, Canada)
Isabelle Kone-Paut (Paris, France)
Brian McCrindle (Toronto, Canada)
Moderators: Cristina Maggio (Palermo, Italy) Alessandra Marchesi (Rome, Italy)
- CLASSIC KD – Maryam Piram (Montreal, Canada)
Rash and peeling: how to distinguish among different conditions such as measles, mononucleosis, Stevens Johnson, So JIA, …Conjunctivitis: how to distinguish among different conditions - INCOMPLETE/ATYPICAL KD – Teresa Giani (Florence, Italy)
Illustrate the diagnostic algorithm for incomplete presentationsHighlight the red flags of atypical presentations - IMAGING – Laura Greco, (Bologna, Italy)
Understand different imaging requirements/findings related to different KD mimics:Lymphadenopathies, retropharyngeal abscessGallbladder, liver
Moderators:
Andrea Donti (Bologna, Italy), Anna Balducci (Bologna, Italy)
Introduction: Basic echocardiography findings and non-findings – Nagib Dahdah (Montreal, Canada)
Live Echocardiography Hands-on for Coronary Artery imaging – Marianna Fabi (Bologna, Italy)
- Where to find the CA, acoustic windows and views (per segments)
- Where and how to measure CA diameter
- Echo machine settings / choice of probes
Moderators:
Marco Cattalini (Brescia, Italy), Giovanni Calabri (Florence, Italy)
RESISTANT KD – Isabelle Melki (Paris, France)
- Illustrate adjuvant treatment options
- Illustrate whether risk factors should prompt primary adjuvant therapy
- Illustrate delayed initial presentation and late diagnosis: to treat or not to treat
MAS AND KD – Francesa Minoia (Milan, Italy)
- Illustrate MAS clinical/lab red flags
- Define treatment options for MAS
MIS-C – Perrine Dusser-Benesty (Paris, France)
- Illustrate MIS-C clinical/lab/radiology red flags
- Define treatment differences and similarities with KD (shock and CAA matters)
Friday / 3 november 2023
Brian McCrindle (Toronto, Canada)
Isabelle Kone-Paut (Paris, France)
Marianna Fabi (Bologna, Italy)
Teresa Giani (Florence, Italy)
Dignitaries
Parents and family associations greetings
Moderators:
Teresa Giani (Florence, Italy)
Nagib Dahdah (Montreal, Canada)
William Orr (St. Louis, USA)
Speakers:
- Long-Term Outcomes after the Multisystem Inflammatory Syndrome In Children: MUSIC Study-RECOVERY – Jane Newburger (Boston, USA)
- Dutch Consortium – Kawasaki Disease Study – Stejara Netea (Amsterdam, The Netherlands)
- Turk MIS-C Study Group – Seza Ozen (Ankara, Turkey) Virtual
- REMKALATINA – Rolando Ulloa Gutierrez (San Jose, Costa Rica) Virtual
- Japanese Kawasaki Disease Study/ AMED Program – Yoshihide Mitani (Japan) Virtual
- Kawarabi – Mona El Ganzoury (Cairo, Egypt) Virtual
Moderators:
Dirk Foell (Muenster, Germany)
Ashraf Harahsheh (Washington DC, USA)
Marija Jelusic (Zagreb, Croatia)
Title:
Kawasaki Disease and IL-1 pathway
Speakers:
Moshe Arditi (Los Angeles, CA) Insights from animal models
Isabelle Kone-Paut (Paris, France) Insights from clinical practice
Moderators:
Michael Portman (Seattle, USA)
Jordi Anton (Barcelona, Spain)
Luigi Lovato (Bologna, Italy)
Speakers:
-
Pathogenesis of MIS-C/KD
Speaker Christoph Kessel (Muenster, Germany) -
New therapeutic targets
Speaker Jane Burns (San Diego, USA) -
Inflammation and the coronary/systemic arteries (KD, MIS-C, vasculitides)
Speaker Simon Lee (Chicago, USA) -
Inflammation and the myocardium in MIS-C (KD, and other types of myocarditis)
Speaker Supriya Jain (New York, USA)
Moderators:
Elisa Fernandez Cooke (Madrid, Spain)
Pei-Ni Jone (Chicago, USA)
Giorgia Martini (Padua, Italy)
Speakers:
Debate 1 – KD patient with small CAA
Pro – KD patients with small CAA should be followed in cardiology clinics – Seda Tierney (Palo Alto, USA)
Con – KD patients with small CAA need not be followed in cardiology clinics – Nilanjana Misra (New York, USA)
Debate 2 – MIS-C in relation to KD
Pro – MIS-C is just a specific form of KD –Angelo Ravelli (Genoa, Italy)
Con – MIS-C is a condition distinct from KD –Fabrizio de Benedetti (Rome, Italy)
Moderators:
Marianna Fabi (Bologna, Italy)
Deepika Thacker (Wilmington, USA)
-
How do we manage the acute KD patient with evolving coronary artery aneurysms?
Case presenter: Brian McCrindle (Toronto, Canada)
Discussant: Therese Giglia (Philadelphia, USA) -
How do we distinguish and manage myocarditis associated with MIS-C from other causes of myocarditis?
Case presenter: Simona Marcora (Milan, Italy)
Discussant: Nadine Choueiter (New York, USA) -
Does artificial intelligence/machine learning help in recognizing incomplete KD from other febrile illnesses? Does AI/ML help distinguish MIS C and KD?
Case presenter: Tyler Harris (Pittsburgh, USA)
Discussant: Cedric Manlhiot (Baltimore, USA) -
How do we define MAS in the setting of KD and MIS-C?
Case presenter: Jordi Anton (Barcelona, Spain)
Discussant: Taco Kuijpers (Amsterdam, The Netherlands
Moderators:
Supriya Jain (New York, USA)
Gabriele Simonini (Florence, Italy)
Alessandra Baldinelli (Ancona, Italy)
Presenters:
TBD
Brian McCrindle (Toronto, Canada)
Isabelle Kone-Paut (Paris, France)
Patient/Parent Perspective
Thanks to:
Saturday / 4 november 2023
Brian McCrindle (Toronto, Canada)
Isabelle Kone-Paut (Paris, France)
Patient/Parent Perspective
Moderators:
Marianna Fabi (Bologna, Italy)
Jean Ballweg (Grand Rapids, USA)
-
What is the optimal thromboprophylaxis strategy for KD or MIS-C patients with large aneurysms?
Case presenter:
Todd Nowlen (Phoenix, USA)
Discussant:
Michael Portman (Seattle, USA) -
What is the significance and prognosis of non-coronary artery systemic aneurysms after KD?
Case presenter: Luis Martin Garrido (Mexico City, Mexico)
Discussant: William Orr (St. Louis, USA) -
What long-term conditions may be triggered by KD or MIS-C? Allergy, autoimmunity, neurodevelopmental, other?
Case presenter: Geetha Raghuveer (Kansas City, USA)
Discussant: Alexandre Belot (Lyon, France) -
What is the significance for MIS-C patients who have persistent abnormalities/LGA on cMRI? Coronary artery abnormalities?
Case presenter: Aurelio Secinaro (Rome, Italy)
Discussant: Ashraf Harahsheh (Washington DC, USA)
Moderators:
Álvaro Lafuente Romero (Madrid, Spain)
Gašper Markelj (Ljubliana, Slovenia)
Lucia Mauri (Milan, Italy)
Kate Webb (Cape Town, South Africa)
Speakers: TBD
Brian McCrindle (Toronto, Canada)
Isabelle Kone-Paut (Paris, France)
Marianna Fabi (Bologna, Italy)
Teresa Giani (Florence, Italy)
Parents Association
Patronages
Speakers
Organizing Committee
Hospital for Sick Children
University of Toronto
(Toronto, Canada)
Kremlin-Bicetre Hospital
University of Paris Saclay
(Paris, France)
Policlinico Sant'Orsola
University of Bologna
(Bologna, Italy)
AOU Meyer Children’s Hospital
University of Florence
(Florence, Italy)
Program Committee
Paris, France
Montreal, Canada
London, UK
Bologna, Italy
Madrid, Spain
Muenster, Germany
Florence, Italy
Washington DC, USA
New York, USA
Barcelona, Spain
Paris, France
Amsterdam, The Netherlands
Madrid, Spain
Honorary President,
Bologna, Italy
Toronto, Canada
Amsterdam, The Netherlands
Ankara, Turkey
Kansas City, USA
Moderators
Policlinico Sant'Orsola
University of Bologna
(Bologna, Italy)
Azienda Ospedaliero Universitaria delle Marche
(Ancona, Italy)
Helen DeVos Children’s Hospital
(Grand Rapids, USA)
(Florence, Italy)
I graduated in Medicine and Surgery in Jul 1996 in University of Florence.
Then I specialized in Pediatrics in University of Florence/Italy in October 2000
In 2005 I earned my Master degree in Pediatric Cardiology, Università degli Studi di Bologna/Italy
Since 2005 I have been working in Cardiology Unit - Meyer Hospital/Florence
University of Brescia and ASST Spedali Civili di Brescia
(Brescia, Italy)
Policlinico Sant'Orsola
University of Bologna
(Bologna, Italy)
Hospital 12 de Octubre
(Madrid, Spain)
University of Muenster
(Muenster, Germany)
Children Hospital "G. Di Cristina", ARNAS Palermo
University of Palermo
(Palermo, Italy)
- "Centro di Riferimento Regionale per le Malattie Rare autoinfiammatorie — Febbri periodiche" of Sicily
- "Centro di Riferimento Regionale per le Malattie del sistema osteomuscolare e del tessuto connettivo in età Pediatrica" of Sicily.
She is the medical referent in Children Hospital “G. di Cristina”, ARNAS Palermo of children with Kawasaki disease and MIS-C.
She is the medical referent of the association “REMARE onlus”, an association of young patients with rheumatologic diseases, autoinflammatory diseases, Kawasaki disease.
She was member of the scientific or organizing committee of several congresses in the field of paediatric rheumatology and she was speaker of lectures about Kawasaki disease, in several national and international congresses.
She is PI of national and international studies and the local PI of PRINTO and of the “Registro internazionale per le iperinfiammazioni da COVID-19 nei bambini e adolescenti”(Cod.: HyperPED-COVID).
She is author of several pubblications in the field of paediatric rheumatology and Kawasaki disease, autoinflammatory diseases, MIS-C, endocrine disorders in paediatric age.
Ospedale Pediatrico Bambino Gesù
(Rome, Italy)
I coordinated the working group for "Italian Guidelines for Kawasaki disease", published in 2008. Then I coordinated the revision of the same, published in August 2018 "Kawasaki disease: guidelines of the Italian Society of Pediatrics, part I and part II”.
Ljubljana University Medical Centre
(Ljubljana, Slovenia)
Department of Woman and Child Health Padua
University of Padua
(Padua, Italy)
Univeristy Hospital Centre
(Zagreb, Croatia)
Hospital Universitario La Paz
(Madrid, Spain)
Policlinico Sant'Orsola
University of Bologna
(Bologna, Italy)
Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico di Milano
(Milan, Italy)
Washington University
St. Louis Children's Hospital
(St. Louis, USA)
Lurie Children's Hospital, Northwestern University Feinberg School of Medicine
(Chicago, USA)
Banner Children's at Desert Medical Center
(Phoenix, USA)
Rheumatology Unit, ERN ReCONNET center, Meyer Children's Hospital IRCCS
University of Florence
(Florence, Italy)
Nemours Childrens Health, Delaware
(Wilmington, USA)
Red Cross Children’s Hospital
University of Cape Town
(Cape Town, South Africa)
Speakers
Hospital Sant Joan de Déu
Universitat de Barcelona
(Barcelona, Spain)
Cedars Sinai Medical Center
UCLA School of Medicine
(Los Angeles, USA)
Hôpital Femme Mère Enfant / Hospices Civils de Lyon
University of Lyon 1
(Lyon, France)
Rady Children's Hospital
UCSD
(San Diego, USA)
Mount Sinai Kravits Children's Hospital
Icahn School of Medicine at Mount Sinai
(New York, USA)
(Verona, Italy)
CHu Sainte-Justine
University of Montreal
(Montreal, Canada)
Ospedale Pediatrico Bambino Gesù
(Rome, Italy)
CHU Kremlin Bicêtre
Paris-Saclay
(Paris, France)
Two fellowships:
- in pediatric rheumatology department of CHU Bicêtre (University of Paris Sud) in France (2014-2016)
- in the pediatric Immunology-Rheumatology department of CHU de Vaud (University of Vaud) in Switzerland (2016-2017).
- In 2022, a MPH degree at University Paris Sud with a program devoted to childhood exposure and risk of developing rheumatoid arthritis in adulthood.
- I currently work as an associate professor in the department of pediatric rhumatology, in the French national reference center for auto-inflammatory diseases (CéReMAIA), in CHU de Bicêtre in Kremlin Bicêtre France (University Paris Saclay, Paris Sud).
I have two main areas of research are auto-inflammatory diseases, especially Chronic Recurrent Multifocal Osteomyelitis and Musculoskeletal pediatric ultrasound.
Ain Shams University
(Cairo Egypt)
Hospital Angeles Lomas
(Mexico City, Mexico)
seeing Kawasaki disease patients since 1996
Member of REKAMLATINA (Red Latinoamericana para la Enfermedad de Kawasaki)
Member of IKDR
Children's Hospital of Philadelphia
University of Pennsylvania
(Philadelphia, USA)
Policlinico Sant'Orsola
University of Bologna
(Bologna, Italy)
Children's National Hospital
The George Washington University School of Medicine & Health Sciences
(Washington DC, USA)
UPMC Childrens Hospital of Pittsburgh
University of Pittsburgh SOM
(Pittsburgh, USA)
New York Medical College/ Maria Fareri Children’s Hospital at Westchester Medical Center
New York Medical College
(New York, USA)
Director of Pediatric Cardiac MRI/Advanced Cardiovascular Imaging at Maria Fareri Children’s Hospital at WMC. Pediatric cardiologist at Boston Childrens Health Physicians, NY.
Clinical Education Liaison, Director of Transition to Residency and Transition to Fourth Year Program at NYMC-School of Medicine.
Steering committee member, IKDR and Scientific committee member of the joint meeting. Also serve on the leadership committee of the American Academy of Pediatrics and Society of Cardiovascular Magnetic Resonance.
Principal Investigator of MACiV -Myocarditis After COVID Vaccination, a large multi-center study funded by the FDA.
Department of Pediatric Rheumatology & Immunology
University of Muenster
(Muenster, Germany)
Amsterdam UMC (Emma Children's Hospital)
University of Amsterdam
(Amsterdam, The Netherlands)
Ann & Robert H. Lurie Children's Hospital
Northwestern Feinberg School of Medicine
(Chicago, USA)
Johns Hopkins University
(Baltimore, USA)
Hôpital Robert-Debré - APHP
(Paris, France)
Fondazione IRCCS Ca' Garanda Ospedale Maggiore Policlinico
(Milan, Italy)
My research is mainly focused on systemic juvenile idiopathic arthritis, macrophage activation syndrome and hemophagocytic syndormes.
I'm the current Secretary and Lead of Clinical Care of the MAS/sJIA Working Party of PReS
Cohen Children's Medical Center of NY, Northwell Health
Zucker School of Medicine (ZSOM)
(New York, USA)
ASST Grande Ospedale Metropolitano Niguarda
(Milan, Italy)
Mie University Hospital
Mie University Graduate School of Medicine
(Tsu, Japan)
President, Japanese Society of Kawasaki Disease.
Chair of International Affairs, Japanese Society of Pediatric Cardiology and Cardiac Surgery.
Liaison member of Young Hearts (AHA)
Postdoctoral training (1997-99) in the Hospital for Sick Children, Toronto.
Amsterdam UMC (Emma Children's Hospital)
(Amsterdam, The Netherlands)
Boston Children's Hospital
Harvard Medical School
(Boston, USA)
Phoenix Children's
University of Arizona
(Phoenix, USA)
Hacettepe University
(Ankara, Turkey) Virtual
My main research interests are childhood vasculitides (including Kawasaki disease) and autoinflammatory diseases (including Familial Mediterranean Fever. I have authored >500 papers, and given many lectures, mainly on these topics.
CHU Sainte Justine
Université de Montréal
(Montreal, Canada)
Seattle Children's
University of Washington
(Seattle, WA)
Children's Mercy Hospital
University of Missouri
(Kansas City, USA)
IRCCS Istituto Giannina Gaslini
University of Genoa
(Genoa, Italy)
Ospedale Pediatrico Bambino Gesù
(Rome, Italy)
His clinical work and research are focused on Cardiovascular MR and CT in children and congenital heart disease.
He started CMR/CT more than a decade ago, after completing his training at Great Ormond Street Hospital for Children in London
His dedication to Cardiovascular Imaging is unyielding and since 2018 he has lead a team of Cardiologists and Radiologists involved in the field.
Dr Aurelio Secinaro actively promotes the clinical role of CMR/CT being part of local, European and global Imaging working groups/task forces and as a member of the Editorial Board of the Journal of Thoracic Imaging and the Congenital Heart Disease Journal.
Lucile Packard Children’s Hospital
Stanford University
(Palo Alto, USA)
Hospital Nacional de Niños de Costa Rica
Universidad de Ciencias Médicas (UCIMED)
(San Jose, Costa Rica)
Virtual
Venue
Auditorium Enzo Biagi, Biblioteca Salaborsa, Piazza del Nettuno,1
All sessions of the 1st IKDR & EUROKiDs Joint Meeting will be held at the Enzo Biagi Auditorium inside the SalaBorsa Library in Bologna. The Auditorium capacity is 150 people.
Inaugurated in 2001, this space was born inside the very important Palazzo d’Accursio, once the seat of the city government. The building overlooks Piazza Nettuno, one of the most beautiful squares in the city, built in 1564.
Sala Borsa was previously the seat of some municipal offices, however between 1988 and 1990 the decision was taken to transform it into a modern cultural center through the inclusion of a library. This decision was made in relation to the urban project called “Urban Park of Piazza Maggiore”, implemented precisely in those years.
In the vicinity of the building there is also the famous covered square, named for the large crystal roof that covers it. Here you can admire the suggestive excavations that testify the presence of the ancient civilizations that have followed one another over the centuries.
Accomodation
Thanks to the agreement with Bologna Welcome, the participants in the Meeting will be able to take advantage of a minimum discount of 10% on the hotel rates applied by the partner structures.
The discount applies to overnight stays from 1 to 5 November 2023 booked on the bookingbolognawelcome.com website by indicating the discount code KAWA23.
Carrying out the search the hotels that have granted the discount will be displayed. By following the various steps of the booking you will arrive at the final confirmation.
Registration
You may register through the form below. Each Participant must use a separate registration form.
The Conference Hall capacity is 150 people.
Letter of Confirmation
A confirmation letter will be sent to the submitted email within one week of receipt of the total registration fee.
Cancellation Policy
Cancellation of registration will be accepted until September 3, 2023, up to which date the registration fee will be refunded with a 50,00.-EUR deduction for administrative expenses.
For cancellations received on and after September 4, 2023, the registration fee will be non-refundable.
Notification of changes in the reservation and/or cancellations must be done in writing to the attention of Ms. Silvia Palmia (s.palmia@projcom.it)
Payment Terms
The official currency of the 1st IKDR & EUROKiDs Joint Meeting is EUR.
Payments should be made in advance via bank transfer.
Social Meeting Dinner
Date: November 3, 2023 – Friday
Venue: TBD
The Social Meeting Dinner is an optional ticket event organised in an offsite venue. The tickets can be purchased through the registration system. Due to limited capacity, only the participants who first purchased tickets will be able to be accepted to attend.
Registration fee includes:
- Access to the Scientific sessions of the meeting
- Congress kit
- Certificate of attendance
- Coffee breaks and Friday lunch
We’re sorry, registration for the meeting is closed
Abstract submission
Instructions:
What can be submitted?
- Original research/unique case reports. Research that has been submitted elsewhere for either presentation or publication elsewhere but has not yet been presented or published prior to November 4, 2023 can be submitted for consideration.
- Submitted research must be relevant to the objectives of the meeting.
What are the requirements for submission?
- Abstracts must be submitted by email by the deadline – Monday, September 11, 2023 by midnight CET to brian.mccrindle@sickkids.ca.
- Corresponding and presenting authors will be informed of acceptance and place in the program before Monday, September 25, 2023.
- It is a requirement that the presenting author of an accepted abstract must register and attend the meeting in person, and at their own expense. This is a requirement for acceptance, and you should consider this before making a submission.
- Authors must choose the presentation type:
– Poster presentation
– Moderated poster presentation. - Please carefully proofread your submission and ensure that it follows the format/instructions exactly and that all requested information is provided.
What is the format for submission?
- All submissions must be in English language.
- Use Arial 12 pt font throughout, single space only.
- Title – Title must not include any abbreviations.
- Authors – Authors should be listed in order and include full name, no degrees.
- Author affiliations – Specify the institutional affiliation for each author. For authors at the same institution the affiliation should be formatted identically.
- Abstract body – Strictly limited to 350 words, including suggested headings. All abbreviations should be initially spelled out in the body of the abstract at first use; the exception is for common abbreviations (such as LV, KD, MIS-C) or accepted measurement units (such as kg, mmol/L). Abstracts with the following structure and headings are preferred:
Background: Highlight the general topic and area of controversy to be addressed.
Study question: This is the question that the study seeks to address, and must be stated as a question (with a question mark [?] at the end).
Methods: This should specify the study population, measurements and data analysis approach aimed at answering the question.
Results: Results much be specified in sufficient detail so as to support the stated conclusions. One small figure or table only can be appended at the end of the abstract which does not count towards the word count.
Conclusions: Conclusions must be supported by the results presented. Inclusion of a statement of clinical relevance is suggested. - At the bottom of the submission, state who is the corresponding/submitting author and their full contact information (full name, mailing address, email). This is the person who will be notified of acceptance and their place in the program. Also state who will be the presenting author if the abstract is accepted (full name, mailing address, email).
Contact
For any question about participation in the meeting, you can contact us using the following form, indicating the subject of your request.